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The PRODH gene is located on chromosome 22q11.21 and is composed of 15 exons that generate two alternatively spliced mRNAs encoding precursor proteins of 600 amino acids (isoform 1) and 492 amino acids (isoform 2)

A 1mM L-cystine stock solution was prepared by dissolving it in 100mM sodium hydroxide and pH was subsequently adjusted to 7.4 with hydrochloric acid

Additionally, they also confirmed the safety of this strategy with respect to brain damage or thrombosis

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Gopel, S

Open questions Considering the characteristics of the heart as a blood-pumping organ, do more intracellular factors need to be considered when targeting NAD+ signals