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The sums of the number of unique ASVs per sample were compared across groups, with the unclassified sequences excluded for the observed ASVs

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Some peptides act as hormone stimulators, while others promote tissue regeneration, immune function, or fat metabolism

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Astrocyte reactivity is associated with increased activity of oxidative enzymes (glutamate dehydrogenase, lactate dehydrogenase, NAD(P)H dehydrogenase, NADH dehydrogenase) [42, 178, 179] which may contribute to ROS mediated toxicity