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Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency

Retatrutide is an investigational peptide drug developed by Eli Lilly that acts as a triple agonist, simultaneously targeting three hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors

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Reducing agents such as dithiothreitol (DTT) and reduced glutathione are commonly used in cell-free reactions to prevent unwanted oxidation