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During pyroptosis, GSDMD-N inserts into the cell membrane, forming cytotoxic pores that compromise membrane integrity and facilitate the release of inflammatory mediators (32)

Trikha A, Baillargeon JG, Kuo YF, Tan A, Pierson K, Sharma G,

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Attenuation of Peripheral Serotonin Inhibits Tumor Growth and Enhances Immune Checkpoint Blockade Therapy in Murine Tumor Models

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