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Wanders RJA, Waterham HR, Ferdinandusse S

Consistently, SIN concentrations in the visceral organs of female rats were markedly higher than those of males, confirming pronounced sex-related differences in its pharmacokinetic and tissue distribution profiles (85)

Cardiomyopathies Ca 2+ channels play a key role in calcium signaling and regulate excitation-contraction coupling in cardiomyocytes, and dysfunction of calcium channels may lead to calcium overload in cardiomyocytes, which in turn may lead to cardiomyopathy [143]

Instead, the presence of MEL under oxidative stress significantly decreased GSSG and increased GSH, reaching similar levels as non-stressed cells ( Figures 4D,E )

Impact of a lactobacilli-containing gel on vulvovaginal candidosis and the vaginal microbiome

It activates cytoprotective mechanisms within cells in a hormetic-type response