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Indeed, several additional metabolic targets of p53 also contribute to its ferroptotic response and the defects in p53-mediated ferroptosis caused by an African-specific polymorphism in the TP53 gene impair its tumor suppressor function [[420], [421], [422], [423]]

PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer

Previous studies indicate that excess androgens in muscle cells can lead to oxidative stress, damaging cell membranes and organelles, increasing the risk of myocyte apoptosis and lysis 43

Methods Enzymol 10 : 245250 Acknowledgements Supported by DGES 97/0054, UCM 6784 181/96 and Fundacin Central Hispano

g , Representative images of intestinal NE morphology in NPP-1::GFP animals grown on cco-1 RNAi bacteria during development or during post-development (start from late L4 or young adult stage) with age

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