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The answer, though, is almost certainly simpler than you think

That triple mechanism is what produced the headline-grabbing results from the Phase 2 NEJM trial, where the 12 mg dose group achieved an average 24.2% body weight reduction over 48 weeks

In such cases, the focus should shift to investigating potential underlying causessuch as myeloproliferative disorders, liver disease, or renal dysfunctionrather than attributing symptoms to the elevated B12 itself

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