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The study also suggested that oxidative stress, a known trigger of eryptosis, may contribute to the membrane alterations observed in RBCs of LC patients

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Non-competitive overactivation of IGF-1R signaling (through mutations) support NSCLC resistance to xentuzumab (BI 836845), a monoclonal antibody targeting both IGF-1 and IGF-2 (72)

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[DOI] [PMC free article] [PubMed] [Google Scholar] DeWire SM, Ahn S, Lefkowitz RJ, Shenoy SK (2007) Beta-arrestins and cell signaling