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In addition, dietary composition impacts tryptophan metabolism
10.1023/b:ddas.0000004520.71462.c9 Dig
Characteristic features of hyperhomocysteinemia are a high plasma homocysteine level and an associated early onset of coronary artery disease (CAD)

It is characterized by short-term memory loss and hallucinations, known as Korsakoff Psychosis, as a consequence of permanent brain damage (, )
HER2 overexpression and PI3K/Akt overactivation also determine increased sensitivity to FASN suppression-induced tumor cell death (215)

Reduced activity of BACH transcription factors may be implicated in the pathogenesis of anemia of inflammation and myelodysplastic syndrome