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Finally, report with rigor so decisions are reproducible and mechanism-anchored: adhere to Methods for ROS detection: techniques, limitations and pitfalls section standardsinclude specificity controls (SOD/catalase, chelators), calibrations and kinetic context and compartment targetingso that therapeutic readouts map cleanly to species, source and location, allowing precise titration rather than blanket scavenging or untargeted escalation

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Feb 8 2024;45(2):1173-1184

Recent studies have revealed that the penta-span transmembrane glycoprotein Prom1 confines glycoprotein 130 (gp130) to lipid rafts and subsequently facilitates the activation of the IL6-gp130-STAT3 signaling pathway during liver regeneration

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