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This approach accurately predicts the cardiotoxicity and other adverse effects of artemisinin derivatives, highlighting its utility in preclinical drug safety evaluation in cancer therapy [99, 100]
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They may be divided into two categories: Schnabel (1981) I)Internal impurities, which may contain chromophoric groups that are introduced into macromolecules during polymerization processing and storage

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The most studied and celebrated among them is GHK-Cu skin transformation, often referred to as copper GHK or copper GHK peptide