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In addition, differences in the initial situation of gastric emptying, which is a measure of the effectiveness of GLP- 1- receptor co-agonists, are likely to have a different effect on patients with obesity than on people in whom preoperative intragastric food retention after taking GLP- 1 receptor co-agonists is not impaired, and in people with diabetes [127]

Colloids Surfaces B Biointerfaces 245, 114249

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Despite promising effects of GluN2B antagonists in HD and other NMDA excitotoxic disease models, there are still limitations, namely 1) potential inefficacy of GluN2B antagonism without additional potentiation of GluN2A and subsequent cell survival signaling