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The weight loss effect depends specifically on AMY1R and AMY3R activation, as confirmed by a study in eBioMedicine that showed cagrilintide lowers body weight through these specific receptor subtypes in the brainstem

2018;72:AP158
doi: 10.1016/j.jconrel.2022.02.028

Katrina Wilhelm, ND is a board-certified naturopathic physician with a passion for functional medicine