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doi: 10.1038/s41467-020-16347-w

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A range of drugs directed towards the treatment of IC have been the topic of recent debate, although the largest percentage of patients cured of the condition remains in the region of 60% [5]

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Some studies suggest that the resistance mechanisms of c-MET inhibitors usually fall into one of two categories: (i) target resistance mediated by secondary MET kinase domain mutations and/or allele amplification of METex14

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