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Description
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The same shuttling system can also export excess acetylcarnitine out of the mitochondria to limit inhibition of pyruvate dehydrogenase and spare the pool of free CoA necessary for other molecules

R.et al (2003)

Funding This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors

[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Staud R

Taken together, these findings suggest that carnitine pool homeostasis is closely related to inflammatory and immune homeostasis, tumor development, and immune escape, providing new perspectives and potential targets for the treatment of inflammatory diseases and cancer
