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NSAID Risks Gastric Ulceration NSAIDS can cause GI ulcer because they block the housekeeping activity of PGE2 but selective COX-2 inhibitors should not because they only block PGE2 in inflammatory or cancerous states they don't affect the gastric mucosa

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This urgency explains why IV fluids are administered not only in hospitals, but also in ambulances, roadside emergencies, disaster zones, and even active combat settings

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