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644,645 Two phase III trials (EMERGE and ENGAGE) on another anti-A mAb, aducanumab, were stopped due to meeting prespecified futility criteria, although it was later recognized that some assumptions of the analysis were violated and inaccurately predicted the final outcomes

It accomplishes this by slowing down both G.I

doi:10.1016/j.tree.2008.10.006 ^ Cazzonelli C.I

The questions were extensive, so a red herring question was asked at the final visit to gauge accuracy and compliance

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