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Once molecular bonds are cleaved or oxidation has occurred, the structural change is irreversible

It's finding something works amazingly, so you double down on it and then it doesn't work

10.1016/S0891-5849(02)01006-7 80 KalanakyS.HafiziM.SafariS.MousavizadehK.KabiriM.FarsinejadA.et al (2016)

For example, being inactive, eating a high-fat diet, smoking, and drinking too much alcohol could lead to health conditions that make you more susceptible to stroke

Legal status (US): Sermorelin has a documented, two-part FDA approval history under the brand name Geref, both approvals held by Serono (later EMD Serono)

doi:10.1152/ajpendo.00712.2009 ^ a b c Berg J.M., Tymoczko J.L., Gatto J.G., Stryer L