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[DOI] [PubMed] [Google Scholar] 264.Wu Y, et al

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Deficiency develops gradually, as the body stores approximately 2-5 mg of B12 in the liver, which can sustain normal function for several years even with inadequate intake or absorption

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6 The reason for mitochondrial dysfunction in ASD is unknown, but the fact that only 23% of children with ASD and MD have a known mitochondrial deoxyribonucleic acid (mtDNA) abnormality suggests that MD may be acquired rather than genetic in many ASD cases