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Cephalalgia 39 , 390402 (2019)

In the control group, the mean hematocrit was 24.0% at baseline and dropped to 21.8% after 12 months

Potential limitations of this study include the short duration, modest sample size, use of a home EEG headband rather than in-lab polysomnography, baseline dietary differences, lack of change on some sleep-related assessment scales, and industry involvement by the extract manufacturer