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Rotating sites may reduce irritation when multiple injections are needed

8 Also in Japan, in 2007, patients with the incurable neurodegenerative disease ALS (Lou Gehrigs disease) received daily injections with 25 mg methylcobalamin for 4 weeks, followed by daily injections of 50 mg intravenously, followed by 50 mg a week

Blood levels remain relatively stable throughout the week even with once-weekly dosing

Below 200 pg/mL is low

Hydroxocobalamin, a nitric oxide scavenger, in the prophylaxis of migraine: an open, pilot study

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