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p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis

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Of particular relevance, this residue is selectively targeted by irreversible EGFR inhibitors, such as afatinib, extensively used in basic research and clinical trials for breast and non-small cell lung cancers [60]

The main SSRIs prescribed for clinical use include fluoxetine, paroxetine, sertraline, and citalopram, among others