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This pearl is partly based on findings from a retrospective review of 160 patients who took one course of isotretinoin compared with 82 patients who underwent two courses

These discrepancies may be explained by the hypothesis that L-carnitine supplementation accompanied by high amounts of carbohydrate intake increases skeletal muscle OCTN2 expression through an insulin-mediated mechanism, thereby increasing skeletal muscle carnitine content [28, 29]

These small variations do not influence the characteristics of the product

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As observed in Herzmann [14], the mean of the plasmatic levels of ALCAR were significantly higher in patients with confirmed HIV-1 infection treated with ALCAR at different dosages than in the control group
