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In order for our bodies to use B12, the form of cobalamin must be converted into methylcobalamin through the MTRR enzyme
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[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Zivanovic-Posilovic G., Balenovic D., Barisic I., Strinic D., Stambolija V., Udovicic M., Uzun S., Drmic D., Vlainic J., Bencic M.L., et al

KPV has shown broad anti-inflammatory activity in various experimental models

The development of 3D culture models and organ-on-chip platforms brought a degree of complexity to classic in vitro for more physiological models of organs including the BBB