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Among the known carnitine transporters, OCTN2 has the highest affinity for carnitine [163]

Binge and crash METH-dosing protocol Binge and crash use of METH is a prevalent form of chronic METH abuse in human METH users involving several drug administrations in a dose-escalation manner on a single day for several days (binge period) followed by a period of abstinence

Some studies suggest that supplementing with L-Carnitine improves cardiovascular function, reduces the risk of heart disease, and lowers cholesterol levels

The body can convert L-carnitine to other amino acids called acetyl-L-carnitine and propionyl-L-carnitine

This suggests that L-Carnitine may have a supportive effect on the proliferation and maintenance of spermatogonia, which are vital for continuous sperm production

Hereditary or acquired defects in the transport mechanisms are the major cause of LC deficiency, leading to pathologies such as cardiomyopathy and skeletal muscle myopathy