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Zhang Z, Zhang X, Yang Y et al (2025) Baicalein protects against heart failure by improving mitochondrial dysfunction and regulating endoplasmic reticulum stress to reduce apoptosis in vitro and in vivo

Currently, some lipid nanoparticles have successfully been transformed from laboratory to industrial production

Both the preclinical study and the clinical trial show the ozone effect as upregulation of antioxidants and downregulation of oxidative stress as well as the crucial cytokines IL-1, Il-6, and TNF-

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Additionally, small-molecule inhibitors, such as retinoic acid receptor-related orphan receptor gamma-t (RORt) inhibitors (e.g., VTP-43742) and tyrosine kinase 2 (TYK2) inhibitors (e.g., deucravacitinib), are currently in development