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21, 22, 32, 33 Cells (15 10 3 ) or primary MM cells (10 4 ) were seeded, incubated with BSO for 24 h and followed by treatment with L-PAM

J Pediatr hematology/oncology

Glutamine is critical for (i) NK cells [191] and Teffs responses, especially Th17 cells and CD8 + T cells, while its absence is associated with Treg cells development in vitro, under Th1-inducing conditions [192,193,194]

The approach was successfully applied to a polar pine nut extract, enabling 40 natural products to be identified, including N -(2-hydroxy-2-carboxymethylsuccinyl)- L-arginine, a metabolite that was previously unreported in food samples

Together, these findings highlight the functional link between GLR-mediated Ca 2+ /NO signalling and mitochondrial stress regulation in plants, suggesting that Arabidopsis can serve as a tractable system to explore conserved principles of mitochondrial dysfunction relevant to neurodegeneration