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[DOI] [PubMed] [Google Scholar] Block ML, Hong JS (2005) Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

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In summary, the results demonstrate that Dihexa is a metabolically stable and BBB-permeable AngIV analog that effectively reverses scopolamine-induced cognitive deficits and improves spatial learning in aged rats

Existing therapies mostly target single pathological links, such as anti-inflammatory or antioxidant actions (Mai et al., 2025)

Individual variability, stemming from genetic factors, existing health conditions, or metabolic differences, plays a significant role
Disrupting the N-glycan interactions affect GluK3 gating properties To test whether these glycan interactions could affect gating properties of GluK3 receptors, we systematically mutated N-glycan sites
