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Bioaccumulation refers to the build-up or steadily increasing concentration of a chemical in organs or tissues in the body

It was demonstrated that the treatment with BEMNs obtained from CagA-positive H

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Notably, while classical organoid systems have long been established exclusively from crypt-resident stem cells 27,28 , our findings challenge this longstanding paradigm by demonstrating that mutation-free villus-derived cells can indeed establish organoids via fetal reversion, revealing remarkable regenerative flexibility of the adult intestinal epithelium