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doi: 10.3389/fnagi.2022.976316 163 WangS.LvD.JiangS.JiangJ.LiangM.HouF.et al
Hepatic, drug-metabolizing cytochrome P450s (CYPs) catalyse the oxidation of tamoxifen to several metabolites
The single study showing decreased b12 levels involved a specific high-risk population
A., Wolchok J
While many patients initially respond to induction chemotherapy, a substantial proportion eventually experience relapse, often with a more aggressive disease phenotype and reduced responsiveness to subsequent treatments
