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d , Counterflow transport of [ 3 H]GSSG into WT or 2YA-mutant SLC33A1 reconstituted liposomes preloaded with 10 mM unlabelled GSSG, followed by incubation with 20 M [ 3 H]GSSG for 40 min

P value calculated using a two-tailed Wilcoxon signed-rank test

Each peptide addresses distinct aspects of the bodys response to rapid transformation while avoiding mechanistic overlap with the triple agonist itself

However, different patterns in the up- or downregulation of biomarkers were observed due to different concentrations tested by both laboratories (i.e., tested concentrations range from 0.0050.2 g/cm 2 or 0.19.4 g/cm 2 in Laboratories 1 and 2, respectively)

Both compounds resulted in a slight increase in cells expressing transferrin- and IL-2 receptors [113]

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