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Compound Name: L-Glutathione

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Targeting cancer stem cells and signalling pathways through phytochemicals: A promising approach against colorectal cancer

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doi: 10.1126/science.179.4073.588

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In fact, DNA methylation has been described in many studies involving tamoxifen resistance, identifying two main mechanisms of resistance: downregulation of estrogen receptor (ER) expression and abnormal activation of the PI3K/AKT/mTOR (mammalian target of rapamycin) signaling pathway [149]

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