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In summary, given that genetic and pharmacologic elevation in O -GlcNAc levels in cultured adipocytes and mouse models is associated with insulin-resistant phenotypes, it is likely that reducing O -GlcNAc levels in adipocytes should reverse the HBP-induced insulin resistance

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doi:10.3109/08958378.2013.779767 Gould NS, Min E, Gauthier S, Chu HW, Martin R, Day BJ (2010) Aging adversely affects the cigarette smoke-induced glutathione adaptive response in the lung

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