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Experimental & Molecular Medicine, 50 (7), 1-13

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-Galactosidase is a hydrolytic lysosomal enzyme that catalyzes the cleavage of -glycosidic bonds between galactose residues and their associated aglycones

Notably, the knockout of the HDAC3 gene or the use of HDAC3 inhibitors can effectively alleviate the inhibition of GPX4, ferroptosis, and renal function damage associated with fibrosis (Zhang L