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Thus, once MTHFR has reduced 5,10-methyleneTHF to 5-MTHF, the Vitamin B12 dependent methionine synthase, encoded by MTR, uses this reduced folate to convert Hcy back into methionine

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These injuries generally occur when a muscle is overexerted or subjected to sudden mechanical shock (44), frequently linked to the overstretching of muscle fibers

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