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J., Yaghi O

In this review we will address how (i) cellular H 2 O 2 is produced and how it regulates certain signaling pathways, (ii) tumor cells cope with enhanced H 2 O 2 levels to escape from oxidative stress, (iii) potential redox-sensors might be correlated with tumorigenesis, and how (iv) H 2 O 2 -modulated processes/pathways might be used as therapeutic targets