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[PubMed] [Google Scholar] 18.Doping in sports: cardiovascular effects

Nat Commun 10: 181, 2019

In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]

FIGURE 2 In addition to be influenced by total intake of TMA precursors, TMAO levels can also be reduced by some bioactive compounds in nutrients

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