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Shils, J
Related to the Principle of Acid-Base Mediocrity is the Principle of Pressure Mediocrity (high pressure flows to low pressure, to give a mediocre pressure) and the Principle of Concentration Mediocrity (high concentration diffuses to areas of low concentration to give a mediocre concentration)
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Whether the research focus is metabolic, body composition, or exploratory, the core principles remain: Start low: 0.5 to 1 mg is a safe starting dose
