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Pro-inflammatory cytokines including IL-12, IL-17, IL-18, IFN, CXCL9, CXCL10, and TNF, and anti-inflammatory cytokines including IL-4, IL-10, and TFG were studied

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How does AOD 9604 work (mechanism of action) While full mechanistic clarity is still under investigation, here are the main proposed/examined pathways: It stimulates lipolysis (the breakdown of stored triglycerides into glycerol + free fatty acids) in fat cells (adipocytes)

The mean fluorescence intensity of CellROX was significantly higher in immune cells from TLS than those from the spleen or peripheral blood (Supplemental Figure 4)

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