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doi:10.1016/S0140-6736(21)01751-7 DAscanio AM, Mullally JA, Frishman WH

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Chiba, T

Among them, the cytosolic enzyme nicotinamide N-methyltransferase (NNMT) has been newly discovered to regulate the levels of nicotinamide precursors required for NAD+ biosynthesis, and therefore plays a crucial role in regulating the NAD+ salvage pathway and cellular metabolism