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Research in animal models shows activity at approximately 0.5mcg/kg, though human protocols typically use standardized doses in the 1-3mg range regardless of body weight

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I had my 1st shot April 1st 2021

Taking supplements, especially in high doses, can leave a metallic taste in your mouth, especially if they contain the following: A 2021 review suggests that you may also experience a metallic sensation after eating foods fortified with these minerals

Clinical Update 8/26/2024 Conolidine for Pain Does conolidine, the main ingredient in CONOCB2 relieve pain, and is it safe

For more on how a dietary supplement B12 can help, its worth digging into the science