glutathione produced by liver Changes in Content in Diseases: An Update Glutathione-mediated biotransformation in the liver

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Oxidative medicine and cellular longevity, 2016, 2016

However, the bimolecular rate constants for the spontaneous reactions of low molecular mass thiols with hydroperoxides hardly reach 30 M 1 s 1 (Winterbourn and Metodiewa, 7 and 10 8 M 1 s 1 , respectively (Trujillo et al., Statements Author contributions All authors jointly wrote the manuscript

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Non-enzymatic antioxidants involve thiol antioxidants (glutathione, thioredoxin and lipoic acid), vitamin C, vitamin E, carotenoids, natural flavonoids, melatonin and other compounds (selenium) (4)