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Protein structure analysis of mutations causing inheritable diseases

J.MironovA.AllanV

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DMAE:Dimethylaminoethanol:An amazing nutrient that extends the life of cells, inhibits the cross linking of proteins, which gives the skin a tone and firm appearance

Abbreviations CyGlySSP: Protein mixed disulfides with cysteinyl glycine CySSHb: S -Cysteinylated hemoglobin CySSP: S -Cysteinylated proteins DTT: Dithiothreitol -GluCySSP: Protein mixed disulfides with -glutamylcysteine GT: -Glutamyl transpeptidase GSH: Glutathione GSSG: Glutathione disulfide GSSP: S -Glutathionylated proteins HbSSG: S -Glutathionylated hemoglobin HcySSP: S -Homocysteinylated proteins HD: Hemodialysis LMM-SH: Low molecular mass thiols mBrB: Monobromobimane NEM: N -Ethylmaleimide NGAL: Neutrophil gelatinase-associated lipocalin PBS: Phosphate-buffered solution PRP: Platelet-rich plasma P-SH: Protein thiol groups RBCs: Red blood cells ROS: Reactive oxygen species RSSP: S -Thiolated proteins t- BOOH: tert -Butyl hydroperoxide TCA: Trichloroacetic acid References Al-Abed Y, VanPatten S, Li H, Lawson JA, FitzGerald GA, Manogue KR, Bucala R (2001) Characterization of a novel hemoglobin-glutathione adduct that is elevated in diabetic patients

El Rosario University Press (2013) A Shander M Cappellini L Goodnough 2009 Iron overload and toxicity: the hidden risk of multiple blood transfusions Vox Sanguinis