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According to the literature, says Christina OConnor, RD, with Pendulum Therapeutics, [berberine] should be taken approximately 30 minutes before meals to minimize blood sugar spikes and prevent any gastrointestinal side effects. She adds that the maximum dose is 900-1500 milligrams per day, with the doses split up three to four times throughout the day
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10.1200/JCO.2002.20.3.751 18 GeislerJ
