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doi: 10.1212/WNL.0000000000002307 72 MarogianniCSokratousMDardiotisEHadjigeorgiouGMBogdanosDXiromerisiouG

A lack of vitamin B12 doesnt directly lead to weight gain, however, so getting a B12 injection alone wont cause you to lose weight no matter how many times your doctor calls the injection a skinny shot

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Hypothyroidism: If you are someone who is suffering from hypothyroidism, taking L-carnitine can make the symptoms worse

In contrast, studies using the Surf1-KO mice (a model of early-onset partial COX-deficiency) and the COX15 / mice showed no change in COX-activity, percentage COX-deficient fibers, and, importantly, no induction of mitochondrial biogenesis