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10.1007/BF00562807 3 ApiA

pylori activates host macrophages and gastric epithelial cells through its cell wall components (such as lipopolysaccharides and peptidoglycans) and various toxic molecules, inducing the release of inflammatory mediators such as tumor necrosis factor- ( TNF- ), interleukin ( IL-1 , IL-6 , IL-8 ), thereby initiating the innate immune response [21]
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AIFM1 variants associated with auditory neuropathy spectrum disorder cause apoptosis due to impaired apoptosis-inducing factor dimerization

While these findings establish important connections, direct evidence specifically linking miRNA-mediated regulation to neuronal ferroptosis in AD remains limited
