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and by the Reactive Nitrogen Species (RNS) that accompany iNOS induction

All of this causes a decrease in the production of melanin by the melanocytes of the hair bulb

Similarly, superoxide is generated by reverse electron transport at the mitochondrial complex I during reperfusion (Chouchani et al., 2015)

Recently, several studies provided evidence that autophagy is the medium of external factors induced ferroptosis, especially ferroptosis inducers

Upon contraction, XO activity is significantly increased and leads to increased lipid peroxidation, protein oxidation, muscle damage and edema [31]
