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Further trials should conduct better randomization and blinding procedures, recruit more participants, and provide adequate reporting

Its pain free, and I am seeing results in my weight loss quicker than I expected and I am feeling the difference in my energy level and fat loss

Figure 3B shows network estimates of treatment effect on Hb levels for different administration routes compared to the oral route

Common effects: Injection-site reactions (mild redness, slight discomfort) most common Transient headaches (resolved without intervention) Mild fatigue in some subjects (usually early in treatment) No serious adverse events reported Laboratory changes: No significant changes in blood glucose or insulin levels No effects on liver enzymes or kidney function No changes in IGF-1 levels (confirming the absence of a GH rise) No clinically significant changes in other laboratory parameters Phase 2 trials (overweight/obese subjects): Efficacy trials in overweight and obese populations confirmed the favorable safety profile