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In a 2018 review, researchers found evidence that taking 1,000 mcg of B12 and getting B12 injections had similar effects on treating B12 deficiencies
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doi: 10.4161/psb.6.8.15791
The remaining author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
Additionally, increased frequencies of diabetes mellitus, high blood pressure, kidney pathologies, coronary artery disease and raised serum lipids were identified [20]
A systematic review found no acute toxicity in animals and no adverse events across various doses
