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For instance, saponins from Reynoutria japonica are extensively fermented and metabolized by gut microbiota, promoting the growth of beneficial bacteria like Bifidobacterium and Lactobacillus , while suppressing harmful bacteria such as Enterococcus and Escherichia coli

Diabetes Metabolic Syndrome: Clin

Consequently, there is an increase in the secretion of pro-tumorigenic cytokine IL-6 and the production of immunosuppressive factor Galectin that switches inflammatory anti-tumour dendritic cells into pro-tumour dendritic cells, thus leading to immunosuppression that drives tumorigenesis [74]

The reduction in tumor burden can be attributed to the antiproliferative effect of curcumin, which has been shown to interfere with mitogenic signaling and suppress angiogenesis through VEGF downregulation

Chronic Inflammation Inflammation is at the center of nearly every age-related disease
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